Fig. 4. Composition of five samples according to the values in the linearity verification panel (A). If both the CVs% for the imprecision at the level of LLoQ and repeatability are low, the samples close to near LLoQ and ULoQ are available and verified AMI can be extended (B). However, the CVs% are high, the samples near LLoQ and ULoQ are not available and verified AMI can be narrowed. (Reprinted with permission from Clinical and Laboratory Standards Institute from: CLSI. Evaluation of Linearity of Quantitative Measurement Procedures. 2nd ed. CLSI guideline EP06. Clinical and Laboratory Standards Institute, 2020 [12]).
Abbreviations: LLoQ, lower limit of quantitation; ULoQ, upper limit of quantitation; CV, coefficient of variation; AMI, analytical measuring interval.

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