Pharmacogenetics is a rapidly evolving field, and the number of pharmacogenetic tests for clinical use is steadily increasing. However, incorrect or inadequate implementation and use of pharmacogenetic testing in clinical practice may result in an increase in medical costs and adverse patient outcomes. This document contains suggested pharmacogenetic testing guidelines for clinical application, interpretation, and reporting of the results through a literature review and evidence-based expert opinions. The clinical laboratory practice guideline includes clinical pharmacogenetic testing covered by public medical insurance in Korea. Technical, ethical, and regulatory issues related to clinical pharmacogenetic testing are also addressed. This document aims to improve the utility of pharmacogenetic testing in routine clinical settings.
Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines Part 1
1Department of Laboratory Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
2Department of Laboratory Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
3Department of Laboratory Medicine, School of Medicine, Pusan National University, Busan, Korea.
4Department of Laboratory Medicine, Seoul National University Hospital and College of Medicine, Seoul, Korea.
5Department of Laboratory Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
6Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
7Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea.
8Department of Laboratory Medicine, Konyang University Hospital, College of Medicine, Konyang University, Daejeon, Korea.
9Department of Laboratory Medicine, Veterans Health Service Medical Center, Seoul, Korea.
10Department of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
11Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
†These authors contributed equally to this work.
Lab Med Online 2016; 6(3): 119-133
Published July 1, 2016
Copyright © The Korean Society for Laboratory Medicine.